Hyperthyroidism

Contents

Causes

Symptoms

Exams and Tests

Treatment

Outlook (Prognosis)

Possible Complications

When to Contact a Medical Professional

Alternative Names

Hyperthyroidism is a condition in which the thyroid gland makes too much thyroid hormone. The condition is often called overactive thyroid.

Causes

The thyroid gland is an important organ of the endocrine system. It is located at the front of the neck just above where your collarbones meet. The gland makes the hormones that control the way every cell in the body uses energy. This process is called metabolism.

The thyroid gland, a part of the endocrine (hormone) system, plays a major role in regulating the body's metabolism.

Many diseases and conditions can cause hyperthyroidism, including:

• Eating too much of foods that contain iodine
• Graves disease (most common cause of hyperthyroidism)
• Inflammation (thyroiditis) of the thyroid due to viral infections, some medicines, or after pregnancy
• Noncancerous growths of the thyroid gland or pituitary gland
• Some tumors of the testes or ovaries
• Taking too much thyroid hormone
• Getting medical imaging tests with contrast dye that has iodine

Symptoms

Common symptoms include:

• Difficulty concentrating
• Fatigue
• Frequent bowel movements
• Goiter (visibly enlarged thyroid gland) or thyroid nodules
• Hand tremor
• Heat intolerance
• Increased appetite
• Increased sweating
• Irregular menstrual periods in women
• Nervousness
• Restlessness
• Sleep problems
• Weight loss (or weight gain, in some cases)

Other symptoms that can occur with this disease:

• Breast development in men
• Clammy skin
• Diarrhea
• Hair loss
• High blood pressure
• Itchy or irritated eyes
• Itchy skin 
• Lack of, or irregular menstrual periods in women
• Nausea and vomiting
• Protruding eyes (exophthalmos)
• Rapid, forceful, or irregular heartbeat (palpitations)
• Skin blushing or flushing   
• Weakness of the hips and shoulders

Exams and Tests

The health care provider will do a physical exam. The exam may find the following:

• High systolic blood pressure (the first number in a blood pressure reading)
• Increased heart rate
• Enlarged thyroid gland
• Shaking of the hands
• Swelling or inflammation around the eyes

Blood tests are also ordered to measure your thyroid hormones TSH, T3, and T4.

You may also have blood tests to check: 

• Cholesterol levels
• Glucose   
• Radioactive iodine uptake

Treatment

Treatment depends on the cause and severity of symptoms. Hyperthyroidism is usually treated with one or more of the following:

• Antithyroid medications
• Radioactive iodine to destroy the thyroid gland and stop the excess production of hormones
• Surgery to remove the thyroid

If your thyroid is removed with surgery or destroyed with radioactive iodine, you must take thyroid hormone replacement pills for the rest of your life.

Medicines called beta-blockers may be prescribed to treat symptoms such as fast heart rate, sweating, and anxiety until the hyperthyroidism can be controlled.

Outlook (Prognosis)

Hyperthyroidism is treatable. Some of its causes may go away without treatment.

Hyperthyroidism caused by Graves disease usually gets worse over time. It has many complications, some of which are severe and affect quality of life.

Possible Complications

Thyroid crisis (storm) is a sudden worsening of hyperthyroidism symptoms that may occur with infection or stress. Fever, decreased alertness, and abdominal pain may occur. Patients need to be treated in the hospital.

Other complications of hyperthyroidism include:

• Heart problems such as fast heart rate, abnormal heart rhythm, and heart failure
• Osteoporosis

Surgery-related complications, including:

• Scarring of the neck
• Hoarseness due to nerve damage to the voice box
• Low calcium level due to damage to the parathyroid glands (located near the thyroid gland)
• Hypothyroidism (underactive thyroid) 

When to Contact a Medical Professional

Call your health care provider if you have symptoms of hyperthyroidism. Go to an emergency room or call the local emergency number (such as 911) if you have:

• Change in consciousness
• Dizziness
• Rapid, irregular heartbeat

Call your health care provider if you are being treated for hyperthyroidism and you develop symptoms of underactive thyroid, including:

• Depression
• Mental and physical sluggishness
• Weight gain

Source: http://www.nlm.nih.gov/medlineplus/ency/article/000356.htm